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CBD & CBG Cannabinoids in Skincare

CBD & CBG Cannabinoids in Skincare


6 minute read

The benefits of Cannabinoids in Skincare is an exciting new discovery! The Cannabis plant contains over 500 biologically active components, with more than 100 classified as phytocannabinoids. Recent research suggests that these cannabinoids could have a extremely positive impact for skin health.

Hemp, a subtype of Cannabis, is particularly noteworthy for its high levels of Cannabinoids, specifically CBD and CBG. Recently, interest has surged in exploring hemp-based extracts as a safer and potentially more effective alternative to topical corticosteroids for certain dermatoses.

The discovery of cannabinoid receptors on the skin has highlighted the anti-inflammatory, anti-itching, analgesic, wound healing, and anti-proliferative effects of both cannabis and hemp derivatives. So adding cannabinoids like CBD and CBG to skin care could have profound benefits for several issues.

Cannabinoids interact with the endocannabinoid system (ECS), comprising neuromodulatory lipids and receptors throughout the nervous system. The main ECS receptors, CB1 and CB2, respond to endogenous and phytocannabinoids. Notable phytocannabinoids include CBD, CBG, and THC.

In simpler terms, cannabinoids from cannabis/hemp plants interact with a system in your body called the endocannabinoid system. This system has receptors that respond to these cannabinoids, and it helps regulate various processes in your body.

Hemp, characterized by high CBD and low THC levels, offers a non-psychoactive alternative known for its diverse applications.

The ECS's presence in skin components like keratinocytes, melanocytes, and mast cells suggests a role in regulating skin functions. Studies reveal that cannabinoids can influence cell proliferation, alter pain perception, stimulate wound healing, and possess anti-microbial and pruritic properties.

Sebaceous Gland Related Disorders:

For conditions like acne, where excessive sebum production and inflammation occur, non-psychotropic phytocannabinoids such as CBD and CBG show promise in normalizing lipid production, reducing proliferation, and alleviating inflammation in human sebocytes. Clinical studies using a cannabis seed extract cream demonstrated efficacy in reducing sebum production and erythema.

Hair Growth Disorders:

Cannabinoids, known for their anti-inflammatory effects, may have potential in treating hair growth disorders such as alopecia. CB1 receptor agonists have shown benefits in hirsutism and hypertrichosis, while CB1 receptor agonists may address alopecia areata.

 

Skin Tumors:

Studies suggest that cannabinoids, through apoptosis induction and inhibiting angiogenesis, exhibit therapeutic effects on non-melanoma skin cancers like basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Additionally, cannabinoids may have a role in treating melanomas.

 

Melanocytes and Pigmentation Disorders:

The endocannabinoid system's presence in melanocytes indicates a dual effect – inducing melanogenesis at low concentrations and apoptosis at high concentrations. This dual effect may be harnessed for treating conditions like vitiligo and melasma.

 

Wound Healing Properties:

Cannabinoid signaling influence on fibroblast functions, epidermal keratinocytes, and cutaneous inflammation suggests a role in wound healing. Murine data indicates dynamic alterations in CB1 and CB2 expression during wound healing.

 

Cutaneous Inflammation and Immunity:

Topical application of CB1 receptor agonists accelerates epidermal barrier recovery, showing anti-inflammatory effects. This presents a potential therapeutic option for inflammatory skin diseases, including atopic dermatitis, contact dermatitis, and psoriasis.

Epidermal Proliferation:

Cannabinoids' anti-inflammatory and immunomodulatory properties, particularly through CB2 receptors, make them a subject of interest in treating psoriasis. The involvement of cannabinoids in T-cell lymphocyte-mediated immune responses and keratinocyte proliferation is under exploration.

Topical Anti-itching Properties:

Topical endocannabinoids-containing emollients demonstrate significant reduction in pruritus in studies, providing potential relief for dermatologic conditions associated with itching.

Topical Analgesic Properties:

Endogenous cannabinoids and synthetic cannabinoid agonists exhibit antinociceptive and anti-inflammatory effects, suggesting potential in topical analgesic applications.

Skin Barrier Repairing Properties, Dry Skin, and Permeability Enhancement:

Studies indicate that cannabinoids, particularly CB1 and CB2, play a role in skin barrier repair. The endocannabinoid system influences the secretion of lamellar bodies and the expression of differentiation marker proteins, suggesting a potential in addressing dry skin and permeability challenges.

Anti-microbial Effects:

Cannabis sativa has long been known to contain cannabinoids with antibacterial properties, showing potency against methicillin-resistant Staphylococcus aureus (MRSA) strains. Hemp, with its antibacterial cannabinoids, may hold promise in addressing antibiotic resistance.

Advanced Cannabinoid skincare CBD-CBG Body Oil Recipe

Ingredients:

  • 240 grams carrier oil (e.g., jojoba, sweet almond, or coconut oil)
  • 2 grams CBD isolate
  • 1 gram CBG concentrate
  • Vitamin E oil (optional, for added skin nourishment and preservation)
  • Essential oils (choose one variation below based on your skin type):

For Dry Skin:

  • 6 drops (approximately 0.3 grams) of Lavender essential oil
  • 3 drops (approximately 0.15 grams) of Geranium essential oil
  • 3 drops (approximately 0.15 grams) of Frankincense essential oil

For Sensitive Skin:

  • 6 drops (approximately 0.3 grams) of Chamomile essential oil
  • 3 drops (approximately 0.15 grams) of Rose essential oil
  • 3 drops (approximately 0.15 grams) of Calendula essential oil

For Oily or Acne-Prone Skin:

  • 6 drops (approximately 0.3 grams) of Tea Tree essential oil
  • 3 drops (approximately 0.15 grams) of Lemon essential oil
  • 3 drops (approximately 0.15 grams) of Eucalyptus essential oil

Instructions:

  • Harmonize with CBD and CBG: In a double boiler, gently heat 240 grams of your chosen carrier oil. Once warm, add 2 grams of CBD isolate and 1 gram of CBG concentrate, stirring until both cannabinoids seamlessly integrate with the carrier oil. The combination of CBD and CBG is known for its harmonious benefits, offering anti-inflammatory, antioxidant, and skin-balancing properties.
  • Enhance with Vitamin E: Allow the CBD-CBG infused carrier oil to cool to room temperature. Consider adding a few drops (approximately 0.1 grams) of Vitamin E oil during this phase for added skin nourishment and preservation.
  • Balance with Essential Oils: After the mixture cools, add the specified drops (in grams) of essential oils based on your skin type. The essential oils further complement the CBD-CBG blend, offering tailored benefits for different skin needs.
  • Thoroughly Combine: Shake the bottle well to ensure a thorough combination of all ingredients, maximizing the synergistic effects.
  • Patch Test for Safety: Before widespread use, perform a patch test to ensure your skin reacts positively to the DIY CBD-CBG body oil.
  • Application: Apply a small amount of the CBD-CBG body oil to clean, dry skin, and massage gently until fully absorbed.

By combining CBD and CBG with nourishing carrier oils and essential oils, this advanced body oil recipe offers a holistic approach to skincare, addressing various skin types and concerns. The harmonious blend of cannabinoids and botanical extracts may contribute to more healthy and balanced skin care routine.

  • CBD Isolate

    CBD Isolate

    $29.00

    Pure CBD is derived through a meticulous extraction process that removes all other compounds including all cannabinoids, terpenes, and plant matter, leaving behind an oil soluble, crystalline powder that is 99.9% pure CBD. Our CBD isolate is 100% pure cannabidiol… read more

  • Full-Spectrum CBG Concentrate

    Full-Spectrum CBG Concentrate

    $25.00

    Full Spectrum CBG Hemp Concentrate is a dark colored liquid extract with a strong herbaceous or citrus terpene profile. It contains over 50% CBG along with a rare cannabinoid CBC, known as the 'bliss molecule.' This extract can be used… read more

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