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CBDA (cannabidiolic acid) is the original, raw form of CBD found naturally in hemp before it is converted into CBD through heat. Unlike CBD, CBDA interacts with different biological pathways, including serotonin receptors and COX-2 pathways involved in inflammation signaling.
Research on CBDA has explored its potential role in:
Inflammatory response
CBDA has been studied for its ability to influence COX-2 activity, a pathway involved in the body’s natural inflammatory response.
Nausea and serotonin signaling
Research suggests CBDA interacts with 5-HT1A serotonin receptors, which are involved in nausea response and nervous system signaling.
Emerging antiviral research
During COVID-19 research, scientists found that CBDA and CBGA were able to bind to the SARS-CoV-2 spike protein and inhibit viral entry into human cells in laboratory studies. While further research is needed to understand its effects in humans, these findings highlighted the unique biological activity of hemp’s lesser-known cannabinoids.
PURE CBDA delivers a concentrated dose of this single cannabinoid for those looking to explore hemp beyond traditional CBD.
Ideal for:
- Supporting a healthy inflammatory response
- Supporting digestive comfort and nausea pathways
- Exploring advanced cannabinoid supplementation
- Adding a targeted cannabinoid to a broader CBD, CBG, or CBN routine
How to Use
Take PURE CBDA daily as a standalone cannabinoid formula, or combine it with other OGR tinctures to create a more personalized hemp routine.
We recommend adding CBDA to your daily routine for:
- Supporting a healthy inflammatory response
- Supporting the body’s natural stress and immune signaling pathways
- Exploring the unique benefits of hemp beyond traditional CBD
Layer PURE CBDA with your favorite OGR formula to expand your cannabinoid profile and add the unique properties of CBDA to your daily regimen.
Frequently Asked Questions
What is CBDA?
CBDA (cannabidiolic acid) is the original form of CBD naturally produced by the hemp plant. Before CBD exists, hemp produces CBDA. Through heat, CBDA converts into CBD through a process called decarboxylation.
Unlike CBD, CBDA is a unique cannabinoid with its own biological activity and has been studied for its interaction with pathways involved in inflammatory response, serotonin signaling, and immune function.
How is CBDA different from CBD?
CBD and CBDA are closely related, but they are different compounds. CBD is the more commonly known cannabinoid, while CBDA is the original acidic form found in raw hemp.
Research suggests CBDA interacts with different pathways in the body than CBD, making it an interesting cannabinoid for those looking to explore beyond traditional CBD.
Why use a pure CBDA formula instead of a full-spectrum tincture?
Most hemp tinctures are designed around CBD and contain little to no meaningful amount of CBDA. Even full-spectrum formulas typically contain only small amounts of naturally occurring CBDA.
PURE CBDA delivers 1000mg of concentrated CBDA as a single cannabinoid, allowing you to experience this rare compound at a level that is difficult to achieve through traditional hemp extracts.
Use it alone as a targeted cannabinoid formula or layer it with other OGR tinctures to customize your cannabinoid routine.
What is CBDA used for?
CBDA has been studied for its unique activity in the body, including pathways involved in:
• Healthy inflammatory response
• Nausea and digestive comfort
• Serotonin signaling and mood pathways
• The body’s natural immune response
PURE CBDA is designed for those looking to explore one of hemp’s most unique cannabinoids beyond traditional CBD.
Can I take CBDA with CBD, CBG, or CBN?
Yes. CBDA can be taken alone or layered with other cannabinoids.
Many people use PURE CBDA alongside CBD, CBG, CBN, or targeted OGR formulas to create a broader cannabinoid profile and customize their routine.
Is CBDA intoxicating?
No. CBDA is non-intoxicating and does not produce a high.
PURE CBDA contains 0% THC.
How do I take PURE CBDA?
Place oil under the tongue and hold briefly before swallowing.
Take daily as part of your cannabinoid routine or use as needed. PURE CBDA can be used on its own or added alongside other OGR formulas.
How much CBDA is in each serving?
PURE CBDA contains:
• 1000mg total CBDA
• Approximately 8mg CBDA per 0.25 mL
• 120 servings per bottle
Why does CBDA need to be stored properly?
CBDA is the natural acidic form of CBD and is sensitive to heat. Exposure to heat can cause CBDA to gradually convert into CBD.
To preserve the integrity of this unique cannabinoid, store PURE CBDA sealed in a cool, dark place away from heat and direct sunlight.
Who is PURE CBDA best for?
PURE CBDA is ideal for:
• Those who want to explore rare cannabinoids beyond CBD
• Experienced hemp users looking for a targeted single-cannabinoid formula
• Those who want to customize their cannabinoid routine by layering formulas
• Anyone interested in the unique properties of CBDA

Only a Few Drops Needed
Tinctures
Take daily as a standalone cannabinoid formula, or layer with your favorite OGR tincture. Add PURE CBDA alongside CBD, CBG, CBN, or targeted formulas to expand your cannabinoid profile and create a more customized hemp routine.

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